First Use of Antibody and Stem Cell Transplantation to Successfully Treat Advanced Leukemia
November 6, 2009 (Research Reports) - For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options. All fifty-eight patients, with a median age of 63 and all with advanced AML or high-risk myelodysplastic syndrome -- a pre-leukemic condition -- saw their blood cancers go into remission using a novel combination of low-intensity chemotherapy, targeted radiation delivery by an antibody and a stem-cell transplant. Read more. Support for the study was provided by The Leukemia and Lymphoma Society.
The Leukemia & Lymphoma SocietyŽ (LLS) is the world's largest voluntary health
agency dedicated to blood cancer. The LLS mission: Cure leukemia, lymphoma,
Hodgkin's disease and myeloma, and improve the quality of life of patients
and their families. LLS funds lifesaving blood cancer research around the
world and provides free information and support services.
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